Practicum in HS Medical Research M

Unit 1: Processing & Work Expectations -Employability Traits

*Students complete and submit all necessary forms to appropriate institution

*Favorable employee traits: Communication skills (verbal & written) time management, and work ethic.

*Research mentor: education, position, research focus & description, publications, journal titles (see Project)

Unit 2:  Scientific Method &

Scientific Literature

*Sequential steps of the research process:  Research problems & questions, Planning, Design, Data collection, Organization & presentation of data, Data analysis, Interpretation of the evidence, Evaluation and dissemination of the results.

Intro to Research in the Health Sciences, “The Research Process”, Ch 3.

*How to read a scientific article, description & significance of  article components - title, abstract, introduction, methods, results, discussion/conclusion, and references. 

Unit 3: Safety - Facility & Class Training

*Globally Harmonized System(GHS), SDS, EHS

*Chemical & physical hazards

*Awareness of Biological, Chemical, Radiation, Physical & Fire Safety

*BBP, PPE, Engineering & Work practice controls

*Handling & storage of hazardous chemicals & hazardous waste

*Principles of Biosafety; Biosafety Levels 1-4, Biosafety Cabinets

*Students perform Lab Safety Assessment (see Activity)

*Supplement facility safety training: factors to prevent most lab accidents, define PEP, exposures to top 9 common chemicals in lab, basic steps of first aid - Clinical Laboratory Science, Ch2, “Safety: Patient and Clinical Laboratory Practices”

*Chemical & Safety related terms such as:  carcinogen, teratogen, ED50, LD50, LC50, toxicity, potentiation, synergism, CAS number, corrosive, GHS pictograms

Unit 4:  Lab Measurements, Lab Equipment

*Convert metric measurements, describe various types of glassware and use, types of pipettes, electronic balances, types of centrifuges, grades of reagents & water. Clinical Laboratory Science, Ch 6, “Systems of Measurement, Laboratory Equipment, and Reagents” 

Unit 5:  Research Planning

*Literature Reviews & Research, Formulating the research question, Methodological considerations, Research proposals, Sampling, Ethics - Intro to Research in the Health Sciences, Ch 4-6

*Components of Research Plan: Background (description, significance, innovation, hypothesis, aims/objectives), Research Methods (schematic diagram, variables, measurements/data collection, statistics, QC, data management, expected outcome, alternative approaches), Ethics, References, Glossary

Unit 6:  Research Ethics

*Development of human research ethics, Nuremberg Code, Declaration of Helsinki, World Medical Association.  Belmont Report principles and levels of IRB.  Vulnerable populations. Therapeutic vs non-therapeutic research. *Purpose of animal research.  Biological rights of animals, care & treatment of research animals. Role of LAR. Role of IACUC.  Three Rs. BRAD (Biomedical Research Awareness Day)

*Animal Ethics studies: Why Animals are Needed in Research?, Ch7; Ethics of Animal Use, Ch8

*Book Immortal Life of Henrietta Lacks

Unit 7:  Evaluate Scientific Literature

*Adequacy of the literature review, defined aims, appropriate research strategy and methods (internal & external validity, measurements, procedure),evaluation of results and discussion.

Intro to Research in the Health Sciences “Critical evaluation of published research”, Ch23. 

Fall CCA

Unit 8:  Materials & Methods

*Components: Background, Hypothesis/  Objectives/Aims,  Schematic illustration overview of study,   Methods (explanation of procedures will include materials used),                  References,                    Acknowledgements

*Students present to class

Unit 9: Research Statistics

*Measurements/Data Collection

*Statistical tests, descriptive(central tendency tests) and inferential statistics (ie ANOVA); Intro to Research in the Health Sciences, Ch 20

*Explain statistical analysis of research project results: scale of measurement, number and groups compared, descriptive statistics or inferential statistics (or both), use and reason for selection of appropriate statistical tests, presentation of results (table, various graphs).

*Prism GraphPad - graph generator

*Translational research - bench to bedside

Unit 10:  Presentations

*Digital Poster, components prepared for poster format (heading, introduction, methods (illustrations, schematic diagram, images), results (various graphs), conclusions, references, acknowledgements)

*Professional presentations, effective delivery in less than 6 minutes

*Students present to class

*Poster session - students present for mentors, teachers, family, friends

Unit 11:  CV Writing

*Research experience

*Presentations

*Personal statement

Spring CCA

Imbedded Activities:

1. Employability Traits - Course Agreement, discuss student, mentor and teacher expectations; Slides“...Through the Eyes of CEOs:  Employee Traits”

2. Mentor biography oral presentation, APA resources

3. Scientific method exercises from Scientific Method - Stephen Carey, 

Ch 1-5

4. How to Read & Understand a Research Study - Video/questions

5. Pair share - assimilate components of scientific articles

6. Facility Training at UTHealth & UTSA: Safety Awareness & Hazard Communication; Laboratory Safety & Hazardous Waste; Basic Bloodborne Pathogens; Basic Biological Safety Quizzes

7. Supplement facility safety training: Safety Kahoot; GHS/ Chemical Kahoot; Pair Sharing - with one blinded student

8. Lab Safety Assessment -

Student records research lab entry & lab exit protocols, bioagents used, presence of biohazards and lab equipment. 

Research Lab Activities:

a.  Date & Time Log Sheet 

b. Follow professional standards & facility guidelines 

c. Weekly Lab Journal submitted to Turnitin.com – objective documentation and research relevance of lab day

Imbedded Activities:

1. Lab Equipment, Pair Share - with one blinded student

2. Primary sources for Research Plan

3. Steps in Planning & Conducting Research - Video/questions

4. Research Plan (see Project)

5. Research Ethics - video/questions

6. Dr. Klugman’s, History of Research Ethics - narrated lecture/questions

7. Ethics - Kahoot

8. Overview of Clinical Research, powerpoint and Research Jeopardy

9. Laboratory Animal Jeopardy

10. HeLa Google Forms, student slides depictions of particular themes in book

11. Review scientific articles, to include Biological (non-therapeutic), Clinical (therapeutic) and Biomaterials (innovations, design improvements).

Research Lab Activities:

a .Date & Time Log Sheet 

b .Follow professional standards & facility guidelines

c. Weekly Lab Journal submitted to Turnitin.com – objective documentation and research relevance of lab day

Imbedded Activities:

1. Teacher and peer evaluation of Materials & Methods oral presentation

2. Record presentation for student & teacher reference

3.Google Form - in one paragraph describe research project, include significance & potential impact

4.Organizing Quantitative Data - Video/questions

5. Inferential Statistics - Video/questions

6. Student describes their project research statistics 

Research Lab Activities:

a .Date & Time Log Sheet 

b .Follow professional standards & facility guidelines

c. Weekly Lab Journal submitted to Turnitin.com – objective documentation and research relevance of lab day

Imbedded Activities:

1.Provide sample posters and oral presentations

2.Teacher and peer evaluation of poster oral presentation

3. Record presentation for student & teacher reference

4. Provide CV samples

Research Lab Activities:

a .Date & Time Log Sheet 

b .Follow professional standards & facility guidelines

c. Weekly Lab Journal submitted to Turnitin.com – objective documentation and research relevance of lab day

Required Project: 

Mentor Biography Presentation

Required Project:

Research Plan Paper

Required Project: 

Materials & Methods Presentation

Required Project: 

Poster Session Presentation

Cycle 1:

-Professionalism

-Teamwork

-Problem Solving

127.15 (2)(A)

127.15 (2)(B)

127.15 (2)(C)

127.15 (2)(D)

127.15 (2)(E)

127.15 (2)(F)

127.15 (2)(G)

127.15 (2)(H)

127.15 (2)(I)

127.15 (2)(J)

127.15 (2)(L)

Cycle 2:

- Job Seeking Skills

127.15 (2)(A)

127.15 (2)(H)

127.15 (2)(I)

127.15 (2)(J)

127.15 (2)(K)

127.15 (2)(L)

Cycle 3:

-Communication Skills

-Self Management Skill

127.15 (2)(A)

127.15 (2)(B)

127.15 (2)(C)

127.15 (2)(D)

127.15 (2)(E)

127.15 (2)(F)

127.15 (2)(G)

127.15 (2)(H)

127.15 (2)(I)

127.15 (2)(J)

127.15 (2)(L)

Cycle 4:

-Civic and Social Responsibility

127.15 (2)(F)

127.15 (2)(G)

127.15 (2)(H)

127.15 (2)(I)

127.15 (2)(L)